Haemophilus influenzae has a GM1 ganglioside-like structure and elicits Guillain-Barré syndrome.
Autor(es): Mori M; Kuwabara S; Miyake M; Dezawa M; Adachi-Usami E; Kuroki H; Noda M; Hattori T.
Resumo: The authors report a patient with an axonal Guillain-Barré syndrome (acute motor axonal neuropathy) associated with anti-GM1 antibody after Haemophilus influenzae infection. The result of ELISA inhibition studies and cytochemical staining with cholera toxin suggest the presence of a GM1-like structure on the surface of H. influenzae isolated from the patient. A particular strain of H. influenzae may have a GM1-like structure and may elicit an axonal Guillain-Barré syndrome.
Imprenta: Neurology, v. 52, n. 6, p. 1282-1284, 1999
Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Immunology
Data de publicação: 1999
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