Ventilatory management of respiratory failure in patients with severe Guillain-Barre syndrome

Autor(es): Aggarwal A N,Gupta D,Lal V,Behera D,Jindal S K,Prabhakar S


Resumo: Guillain-Barre syndrome (GBS) is the commonest peripheral neuropathy causing ventilatory failure, and 10-30% patients may require respiratory support. Records of 11 adult patients of GBS in respiratory failure, admitted to the Respiratory Intensive Care Unit (RICU) of our institute for mechanical ventilation over a four-year period, were studied. Six patients received intravenous immunoglobulin. The median duration of mechanical ventilation was 38 days. Seven patients underwent tracheostomy. Four patients were ventilated for less than 2 weeks and 3 for more than 2 months each. Seven developed ventilator-associated pneumonia and/or sepsis. Three patients died in, and two shortly after discharge from RICU; all had systemic problems or complications of hospitalization.


Imprenta: Neurology India, v. 51, n. 2, p. 203-205, 2003


Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Epidemiology ; Guillain-Barre Syndrome - Public health


Data de publicação: 2003