Miller Fisher syndrome with presynaptic neuromuscular transmission disorder.
Autor(es): Ehler Edvard; Latta Jan
Resumo: Miller Fisher syndrome is defined by a triad of symptoms, namely areflexia, ataxia, and ophthalmoparesis. The ophthalmoparesis is mostly severe, undulating weakness of eye movements with ptosis and increased fatigability resembling a neuromuscular transmission disorder. We present a 52-year-old man with severe Miller Fisher syndrome with a high level of anti-GQ1b antibodies and a presynaptic type of neuromuscular transmission disorder. The diagnosis was confirmed by stimulated single-fiber electromyography with the use of a concentric needle electrode and various stimulation rates.
Palavras-Chave: Fisher syndrome, Neuromuscular transmission disorder, Ophthalmoparesis, Single-fiber electromyography
Imprenta: Journal of Clinical Neuroscience, v. 21, n. 11, p. 2025-2027, 2014
Identificador do objeto digital: 10.1016/j.jocn.2014.05.050
Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Clinical examination ; Guillain-Barre Syndrome - Transmission ; Guillain-Barre Syndrome - Immunology
Data de publicação: 2014
