Rapidly progressive polymyositis with elevated antiacetylcholine receptor antibody activity.
Autor(es): Yamaguchi Y.; Sakurai Y.; Mannen T.; Shimizu J.
Resumo: We report a 51-year-old woman with polymyositis accompanied by a high titer of antiacetylcholine receptor antibody. The patient presented with weakness of grip strength followed by rapidly progressive dyspnea, which required mechanical ventilation. She was treated with a glucocorticoid and came off the respirator one week later. Antiacetylcholine receptor antibody activity was elevated in the acute phase and decreased during recovery, although other signs of myasthenia gravis were negative. This patient suggested that in cases of rapidly progressive bulbar palsy and limb muscle weakness, it is necessary to include polymyositis associated with elevated antiacetylcholine receptor antibody activity in the differential diagnosis.
Palavras-Chave: Myasthenia gravis; Autoantibody; Autoimmune disease
Imprenta: Internal Medicine, v. 39, n. 12, p. 1108-1110, 2000
Identificador do objeto digital: 10.2169/internalmedicine.39.1108
Descritores: Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Clinical examination ; Guillain-Barre Syndrome - Immunology
Data de publicação: 2000
