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Viral encephalitis in the ICU

Autor(es)Kramer Andreas H
ResumoViral encephalitis causes an altered level of consciousness, which may be associated with fever, seizures, focal deficits, CSF pleocytosis, and abnormal neuroimaging. Potential pathogens include HSV, VZV, enterovirus, and in some regions, arboviruses. Autoimmune (eg, anti-NMDA receptor) and paraneoplastic encephalitis are responsible for some cases where no pathogen is identified. Indications for ICU admission include coma, status epilepticus and respiratory failure. Timely initiation of anti-viral therapy is crucial while relevant molecular and serological test results are being performed. Supportive care should be directed at the prevention and treatment of cerebral edema and other physiological derangements which may contribute to secondary neurological injury.
Palavras-ChaveAcute disseminated encephalomyelitis (ADEM); Anti-NMDA receptor antibodies; Arbovirus; Coma; Encephalitis; Herpes simplex virus; Varicella zoster virus; West Nile virus
ImprentaCritical Care Clinics, v. 29, n. 3, p. 621-649, 2013
Identificador do Objeto Digital10.1016/j.ccc.2013.03.011
DescritoresGuillain-Barre Syndrome - Arbovirus ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Inflammation ; Guillain-Barre Syndrome - Viral infections ; Guillain-Barre Syndrome - Virus ; Guillain-Barre Syndrome - Epidemiology
Data de Publicação:2013