Proposed mechanism of ataxia in Fisher's syndrome.
Autor(es)Ropper A. H.; Shahani B.
ResumoA patient with Fisher's variant of Guillain-Barré syndrome had severe limb ataxia. Joint position sense was diminished proximally but normal distally. In contrast, muscle proprioceptive function, studied electrophysiologically by recording silent periods in proximal muscles, appeared to be normal. A disparity between proprioceptive information from muscle spindles and kinesthetic information from joints and other proprioceptors may be a mechanism of ataxia, based solely on abnormalities of peripheral nerve function. A CNS lesion is, therefore, not necessary to explain cerebellar ataxia in Fisher's syndrome.
ImprentaArchives of Neurology, v. 40, n. 9, p. 537-538, 1983
Identificador do Objeto Digital10.1001/archneur.1983.04050080037004
DescritoresGuillain-Barre Syndrome - Pathogenesis
Data de Publicação:1983
