The risk of Guillain-Barré syndrome after tetanus-toxoid-containing vaccines in adults and children in the United States
Autor(es): Tuttle J,Chen R T,Rantala H,Cherry J D,Rhodes P H,Hadler S
Resumo: This study examined whether there is a risk that tetanus-toxoid-containing vaccines could cause Guillain-Barré syndrome and, if so, how large the risk is. This study was based on previous active surveillance epidemiological studies of Guillain-Barré syndrome and vaccination history. A background rate of 0.3 cases of Guillain-Barré syndrome per million person-weeks has been estimated. By chance, 2.2 people with the syndrome would have received tetanus-toxoid-containing vaccine within the 6 weeks before onset, yet only 1 person had done so. Data on children show similar results. If an association exists, it must be extremely rare and not of public health significance.
Imprenta: American Journal of Public Health, v. 87, n. 12, p. 2045-2048, 1997
Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Vaccine ; Guillain-Barre Syndrome - Epidemiology ; Guillain-Barre Syndrome - Public health
Data de publicação: 1997
