A case of Miller Fisher syndrome with pharyngeal palsy as an initial symptom
Autor(es): Taguchi Y,Takashima S,Inoue H,Kusunoki S
Resumo: We report herein a rare case of Miller Fisher syndrome with pharyngeal palsy as an initial symptom. A 68-year-old man admitted to our hospital with pharyngeal palsy two weeks after a respiratory infection. He subsequently developed ataxic gait, paresthesia in the upper limbs and ophthalmoplegia. Double-filtrated-plasmapheresis had been performed four times and all the symptoms subsided within two months. In the acute phase of the disease, the titers of anti-GQ1b and GT1a antibodies were elevated. The titer of anti-GT1a antibody was higher than that of anti-GQ1b antibody. Recently, the activity of serum anti-GT1a antibody has been supposed to be associated with pharyngeal palsy. In the present case, higher titer of anti-GT1a antibody compared with that of anti-GQ1b antibody could possibly cause pharyngeal palsy as an initial symptom of Miller Fisher syndrome.
Palavras-Chave: Miller Fisher syndrome; Pharyngeal palsy; Anti-ganglioside antibody; Anti-GT 1a antibody
Imprenta: No? to Shinkei = Brain and Nerve, v. 53, n. 3, p. 275-278, 2001
Identificador do objeto digital: 10.11477/mf.1406901743
Descritores: Guillain-Barre Syndrome - DNA ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Immunology
Data de publicação: 2001
