Autor(es): Palanivelu Chinnusamy, Rangarajan Muthukumaran, Rajapandian Subbiah, Maheshkumaar Gobi Shanmugam, Madankumar Madhupalayam Velusamy

Resumo: Jejunal diverticula are rare lesions, - when complications arise, they pose diagnostic difficulties. Perforation is a common complication resulting in an acute abdomen, although preoperative diagnosis is usually not possible. The gold st-ard" for management for patients with complications is surgery. We present a series of patients with perforated jejunal diverticula who were on prolonged treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) - steroids for Chikungunya fever. There were a total of six patients, all of them presenting with perforative peritonitis, with or without shock. Plain abdominal radiogram - ultrasonogram confirmed this, although the exact site of the perforation was not diagnosed preoperatively. All patients underwent exploratory laparotomy - perforated jejunal diverticulum was found. Resection - anastomosis was performed in all cases. The mean operating time was 113.5 minutes, - the blood loss was not significant. Postoperative course was uneventful except wound infection in two patients. There was no mortality. Prolonged NSAID - steroid use are known to cause ulceration/perforation of the upper digestive tract - colonic diverticula. This seems to be the most likely cause for the perforation of jejunal diverticula in our series of patients. This view is supported by the absence of inflammation - infiltration of neutrophils on histopathological examination of the diverticula."

Imprenta: World Journal of Surgery, v. 32, n. 7, p. 1420-1424, 2008, Discussion 1425

Identificador do objeto digital: 10.1007/s00268-008-9469-0

Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Inflammation ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever

Data de publicação: 2008

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