Autor(es): Rudolph Kara E, Lessler Justin, Moloney Rachael M, Kmush Brittany, Cummings Derek A T

Resumo: Mosquito-borne viruses are a major public health threat, but their incubation periods are typically uncited, non-specific, - not based on data. We systematically review the published literature on six mosquito-borne viruses selected for their public health importance: chikungunya, dengue, Japanese encephalitis, Rift Valley fever, West Nile, - yellow fever viruses. For each, we identify the literature's consensus on the incubation period, evaluate the evidence for this consensus, - provide detailed estimates of the incubation period - distribution based on published experimental - observational data. We abstract original data as doubly interval-censored observations. Assuming a log-normal distribution, we estimate the median incubation period, dispersion, 25th - 75th percentiles by maximum likelihood. We include bootstrapped 95% confidence intervals for each estimate. For West Nile - yellow fever viruses, we also estimate the 5th - 95th percentiles of their incubation periods.

Imprenta: The American Journal of Tropical Medicine and Hygiene, v. 90, n. 5, p. 882-891, 2014

Identificador do Objeto Digital: 10.4269/ajtmh.13-0403

Descritores: Chikungunya virus - Flaviviridae ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health

Data de Publicação: 2014