Autor(es): Apandi Y, Lau S K, Izmawati N, Amal N M, Faudzi Y, Mansor Wan, Hani M H, Zainah S

Resumo: Malaysia experienced its first outbreak of chikungunya virus (CHIKV) infection in late 1998 in Klang District in Selangor; six years later the virus re-emerged in the state of Perak. All the CHIKV isolates in 1988 - 2006 shared high sequence similarities - belonged to the Asian genotype. In 2007 - 2008 CHIKV infection again reemerged but the genotype was the Central/East African genotype. This strain was found to be similar to the strains causing outbreaks in the India Ocean. In 2009, the strains circulating in Malaysia, including the state of Kelantan, based on the partial E1 gene, also belong to the Central/East African genotype.

Palavras-Chave: Chikungunya virus; Circulating strain; Genotype; Malaysia

Imprenta: The Southeast Asian Journal of Tropical Medicine and Public Health, v. 41, n. 6, p. 1374-1380, 2010

Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health

Data de publicação: 2010

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