Cutaneous manifestations of chikungunya fever: Observations made during a recent outbreak in south India
Autor(es): Inamadar Arun C, Palit Aparna, Sampagavi V V, Raghunath S, Deshmukh N S
Resumo: Chikungunya fever is an Aedes mosquito-borne Arbo viral illness with significant morbidity. In a recent outbreak of the disease in south India, the dermatologic manifestations of 145 patients attending a tertiary care hospital were recorded. All age groups were affected, including newborns. Some of the cutaneous features were observed during the acute stage of the illness, - others during convalescence or thereafter. Pigmentary changes were found to be the most common cutaneous finding (42%), followed by maculopapular eruption (33%) - intertriginous aphthous-like ulcers (21.37%). Lesions with significant morbidity were generalized vesiculobullous eruptions (2.75%), found only in infants, lymphedema, - intertriginous aphthous-like ulcers. Exacerbation of existing dermatoses, such as psoriasis, - unmasking of undiagnosed Hansen's disease were observed. A perivascular lymphocytic infiltrate was a consistent histopathologic finding in all types of skin lesions. All patients responded well to symptomatic, conservative treatment. The cutaneous findings hitherto not reported may be the result of the African genotype of the virus detected during this outbreak in India.
Imprenta: International Journal of Dermatology, v. 47, n. 2, p. 154-159, 2008
Identificador do objeto digital: 10.1111/j.1365-4632.2008.03478.x
Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health
Data de publicação: 2008
