Autor(es): Villamil-Gómez Wilmer, Alba-Silvera Luz, Menco-Ramos Antonio, Gonzalez-Vergara Alfonso, Molinares-Palacios Tatiana, Barrios-Corrales María, Rodríguez-Morales Alfonso J

Resumo: Congenital chikungunya virus (CHIK) infection has been infrequently reported, even more so during the current 2013-15 outbreak in Latin America. In this study, the consequences of CHIK on pregnancy outcomes - particularly consequences in infants born to infected women were assessed in a case series from a single private institution in the north of Colombia. During September 2014 to February 2015, seven pregnant women with serological - reverse transcription-polymerase chain reaction-positive test for CHIK delivered eight infants with CHIK. These newborns required admission to pediatric intensive care, - related support, owing to severe clinical manifestations, which included respiratory distress, sepsis, necrotizing enterocolitis, meningoencephalitis, myocarditis, edema, bullous dermatitis - pericarditis. There were three deaths (case fatality rate of 37.5%). Pregnant women - newborns with CHIK long term should be followed up, given the implications of chronic sequelae (e.g. chronic inflammatory rheumatism in women) as well as recently described neurocognitive impairment in infants.

Palavras-Chave: Chikungunya; Colombia; Arbovirus; Congenital; Epidemiology

Imprenta: Journal of Tropical Pediatrics, v. 61, n. 5, p. 386-392, 2015

Identificador do objeto digital: 10.1093/tropej/fmv051

Descritores: Chikungunya virus - Arbovirus ; Chikungunya virus - Viral infections ; Chikungunya virus - Serological diagnosis ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health

Data de publicação: 2015

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