CHIKVPRO and a protein sequence annotation database for chikungunya virus
Autor(es): Mishra Akaash Kumar, Jain Chakresh Kumar, Agrawal Apurva, Jain Saransh Jain Kumar Sambhav, Dudha Namrata, Kumar Kapila, Sharma Sanjeev K, Gupta Sanjay
Resumo: In the recent past, there has been a resurgence of interest in Chikungunya virus (CHIKV) attributed to massive outbreaks of Chikungunya fever in the South-East Asia Region. This has reflected in substantial increase in submission of CHIKV genome sequences to NCBI (National Center for Biotechnology Information) database. Hereby we submit a database CHIKVPRO" containing structural - functional annotation of Chikungunya virus proteins (25 strains) submitted in the NCBI repository. The CHIKV genome encodes for 9 proteins:4 non-structural - 5 structural. The CHIKVPRO database aims to provide the virology community with a single accession authoritative resource for CHIKV proteome- with reference to physiochemical - molecular properties, proteolytic cleavage sites, hydrophobicity, transmembrane prediction, - classification into functional families using SVMProt - other Expasy tools. The database is freely available at http://www.chikvpro.info/"
Palavras-Chave: CHIKV; CHIKVPRO; Chikungunya virus; Database; Protein sequence
Imprenta: Bioinformation, v. 5, n. 1, p. 4-6, 2010
Descritores: Chikungunya virus - Genome ; Chikungunya virus - Proteins ; Chikungunya virus - Proteome ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever
Data de publicação: 2010
