Chikungunya, a paradigm of neglected tropical disease that emerged to be a new health global risk

Autor(es): Rougeron Virginie, Sam I-Ching, Caron Mélanie, Nkoghe Dieudonné, Leroy Eric, Roques Pierre


Resumo: Chikungunya virus (CHIKV) is an alphavirus of the Togaviridae family that causes chronic - incapacitating arthralgia in human populations. Since its discovery in 1952, CHIKV was responsible for sporadic - infrequent outbreaks. However, since 2005, global Chikungunya outbreaks have occurred, inducing some fatalities - associated with severe - chronic morbidity. Chikungunya is thus considered as an important re-emerging public health problem in both tropical - temperate countries, where the distribution of the Aedes mosquito vectors continues to exp-. This review highlights the most recent advances in our knowledge - underst-ing of the epidemiology, biology, treatment - vaccination strategies of CHIKV.


Palavras-Chave: Chikungunya


Imprenta: Journal of Clinical Virology, v. 64, p. 144-152, 2015


Identificador do objeto digital: 10.1016/j.jcv.2014.08.032


Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Vaccine ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemiology ; Chikungunya virus - Immunology ; Chikungunya virus - Public health


Data de publicação: 2015