Autor(es): Pfeffer M, Hanus I, Löscher T, Homeier T, Dobler G

Resumo: This report describes the first isolation - molecular characterisation of a chikungunya virus from two German tourists who became ill after a visit to the Maldives in September 2009. The virus contained the E1 A226V mutation, shown to be responsible for an adaptation to the Asian tiger mosquito Aedes albopictus. The E1 coding sequence was identical to chikungunya virus isolates from Sri Lanka - showed three nt-mismatches to the only available E1 nt sequence from the Maldives.

Imprenta: Euro Surveillance, v. 15, n. 13, 2010

Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Molecular screening ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Public health

Data de publicação: 2010