Autor(es): Kumar Naresh C V M, Nadimpalli Mahathi, Vardhan Vishnu R, Gopal Sai D V R

Resumo: Chikungunya virus (CHIKV) an emerging arboviral infection of public health concern belongs to the genus Alphavirus, family Togaviridae. Blood group antigens are generally known to act as receptors for various etiological agents. The studies defining the relationship between blood groups - CHIKV is limited - hence it is necessary to study these parameters in detail. In the present study 1500 subjects were enrolled - demographic data (Age, Gender, Blood group, CHIKV infection status, - CHIKV infection confirmation mode) was collected from them. The risk of acquiring CHIKV disease - its association with factors such as blood group, age - gender was analyzed statistically. The data of this study showed a possible association between blood group, age - gender of the study population with CHIKV infection. It is observed that CHIKV infections were higher in individuals with Rh positive blood group when compared to their Rh negative counterparts.CHIKV infections were found to be higher in Rh positive individuals of AB - A blood groups than that of Rh negative counterparts. Results also indicated that infections were higher in adults belonging to the age group > 30 years - also higher in males as compared to females enrolled in this study. These data present further evidence for the association of the blood groups, age - gender to susceptibility to CHIKV infection. Further studies are needed to confirm these findings. This is the second study showing the possible association of blood groups with chikungunya.

Imprenta: Virology Journal, v. 7, p. 140, 2010

Identificador do objeto digital: 10.1186/1743-422X-7-140

Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Public health

Data de publicação: 2010

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