Autor(es): Taraphdar Debjani, Sarkar Arindam, Mukhopadhyay Bansi B, Chatterjee Shyamalendu

Resumo: Chikungunya virus (CHIKV) - dengue virus (DENV) are circulating individually in the state of West Bengal, India. However, after 1965 the dual-infection caused by both viruses had not been recorded until 2010. In 2010, an investigation of the febrile cases was carried out to confirm the involvement of both viruses simultaneously. A total of 550 blood samples were tested for the detection of immunoglobulin M (IgM) antibody against both CHIKV - DENV. Serology by the enzyme-linked immunosorbent assay method confirmed that 131 (23.8%) - 104 (18.9%) patients had IgM antibody against CHIKV - DENV, respectively, whereas 68 (12.4%) had IgM antibodies against both CHIKV - DENV. Fever, joint pain, rashes, headache, myalgia, - nausea/vomiting are the common features in the case of both monotypic - dual-infection. Severe arthralgia - swelling of joints were common only in CHIKV-positive cases - abdominal pain was mainly associated with DENV infection. Diarrhea was reported only by the dual-infected patients (16.2%).

Imprenta: The American Society of Tropical Medicine and Hygiene, v. 86, n. 4, p. 720-723, 2012

Identificador do objeto digital: 10.4269/ajtmh.2012.11-0704

Descritores: Chikungunya virus - Cytopathology ; Chikungunya virus - Flaviviridae ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - Antibodies ; Chikungunya virus - Serology ; Chikungunya virus - Viral infections ; Chikungunya virus - Serology ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health Chikungunya virus - Cytopathology ; Chikungunya virus - Flaviviridae ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - Antibodies ; Chikungunya virus - Serology ; Chikungunya virus - Viral infections ; Chikungunya virus - Serology ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health Chikungunya virus - Cytopathology ; Chikungunya virus - Flaviviridae ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - Antibodies ; Chikungunya virus - Serology ; Chikungunya virus - Viral infections ; Chikungunya virus - Serology ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health

Data de publicação: 2012

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