Major essential oils composition and immunotoxicity activity from leaves of Foeniculum vulgare against Aedes aegypti L
Autor(es): Chung, Ill-Min; Ro, Hee-Myong; Moon, Huyng-In
Resumo: The leaves of Foeniculum vulgare (Umbelliferae) were extracted and the major essential oil composition and immunotoxicity effects were studied. The analyses conducted by gas chromatography and mass spectroscopy (GC-MS) revealed the essential oils of F. vulgare leaves. The F. vulgare essential oil yield was 0.97%, and GC/MS analysis revealed that its major constituents were methyl clavicol (46.3%), a-phellandrene (18.2%), fenchone (10.6%), (E)-anethole (11.3%), myrcene (3.4%), and alpha-pinene (2.1%). The essential oil had a significant toxic effect against early fourth-stage larvae of Aedes aegypti L with an LC50 value of 41.23 ppm and an LC90 value of 65.24 ppm. Also, methyl clavicol (>= 98.0%), alpha-phellandrene (>= 95.0%), fenchone (>= 98.0%), (E)-anethole (>= 99.0%), myrcene (>= 99.0%), and a-pinene (>= 99.0%) were tested against the F-21 laboratory strain of A. aegypti. Fenchone (>= 98.0%) and (E)-anethole (>= 99.0%) have medium activity with an LC50 value of 73.11 ppm and 102.41 ppm. The above data indicate that major compounds interaction may play a more important role in the toxicity of essential oil.
Imprenta: Immunopharmacology and Immunotoxicology, v. 33, n. 3, p. 450-453, 2011
Identificador do objeto digital: 10.3109/08923973.2010.532805
Descritores: Aedes aegypti - Immunology
Data de publicação: 2011
