Autor(es): Bosire, Carren M.; Deyou, Tsegaye; Kabaru, Jacques M.; Kimata, Dennis M.; Yenesew, Abiy

Resumo: The dichloromethane/methanol (1:1) extract of the stem bark of Millettia usaramensis subspecies usaramensis was tested for its larvicidal activity against the 4th instar Aedes aegypti larvae and demonstrated activity with LC50 value of 50.8 +/- 0.06 mu g/mL at 48 h. Compounds isolated from the extract were also tested for their larvicidal activities, and the rotenoid usararotenoid-A (LC50 4.3 +/- 0.8 mu g/mL at 48 h) was identified as the most active principle. This compound appears to be the first rotenoid having a trans-B/C ring junction and methylenedioxy group at C-2/C-3 with high larvicidal activity. Related rotenoids with the same configuration at the B/C-ring junction did not show significant activity at 100 mu g/mL. (C) 2014 Korean Society of Applied Entomology, Taiwan Entomological Society and Malaysian Plant Protection Society. Published by Elsevier B.V. All rights reserved.

Palavras-Chave: Millettia usaramensis subspecies usaramensis; Aedes aegypti; Larvae; Rotenoid; Usararotenoid-A

Imprenta: Journal of Asia-Pacific Entomology, v. 17, n. 3, p. 531-535, 2014

Identificador do objeto digital: 10.1016/j.aspen.2014.05.003

Descritores: Aedes aegypti - Larvicide ; Aedes aegypti - Public health

Data de publicação: 2014

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