Pharmacological factors in the saliva of blood-feeding insects - Implications for vesicular stomatitis epidemiology
Autor(es): Tabachnick, WJ
Resumo: Vesicular stomatitis (VS) epizootics in the Western United States have caused substantial economic losses to U.S. livestock industries in 1995, 1997, and 1998. The role of arthropods in transmitting VS to U.S. livestock is unclear. In particular, the impact of arthropod salivary gland factors in VS infections in livestock needs study. Pharmacological effects of arthropod salivary gland factors on animals are reviewed. The potential effects of arthropod saliva on the transmission and spread of VS virus to livestock in the Western U.S. is presented with emphasis on the biting midge, Culicoides sonorensis. Information is discussed with attention to vector potential of C. sonorensis, and its use as a model for evaluating insect salivary gland pharmacology on livestock response to VS.
Palavras-Chave: Fly lutzomyia longipalpis; Glossina morsitans morsitans; Cellular immune responses; Mosquito Aedes aegypti; North American vector; Necrosis factor alpha; Coagulation factor-XA; Virus New Jersey; Nitric oxide; Gland extracts
Imprenta: Tropical Veterinary Diseases: Control and Prevention in the Context of the New World Order, v. 916, p. 444-452, 2000
Descritores: Aedes aegypti - Epidemiology
Data de publicação: 2000
