Autor(es)Silva, Flavia Corvello da; Barros, Francisco Maikon; Prophiro, Josiane Somariva; Silva, Onilda Santos da; Pereira, Thiago Nunes; Bordignon, Sergio Ade Loreto; Eifler-Lima, Vera Lucia;Poser, Gilsane Lino von

ResumoIn this study, the larvicidal activity of an enriched fraction of the major lipophilic phenolic compounds from Hypericum carinatum Griseb. (Clusiaceae) was investigated against larvae of Aedes aegypti (Diptera: Culicidae), the main vector of dengue virus in Brazil. The larval mortality rate ranged 37.33 to 72.00 % at concentrations of 66-200 mu g/mL. The effect demonstrated to be dose-dependent. The lethal concentration 50 % and confidence interval were 100 and 88-111 mu g/mL, respectively. The results could be attributed to the presence of cariphenone A and cariphenone B in concentrations of 1.24 plus or minus 0.04 and 0.56 plus or minus 0.01 %, respectively, determined by high-performance liquid chromatography. Besides, the results reinforce the potential of genus Hypericum as source of alternative insecticides.

Palavras-ChaveMolecular structure; Lethal limits; Pesticides; Larvae; Hosts; Mortality causes; Public health; Mortality; Insecticides; Benzophenone; Phenolic compounds; Vectors; Lipophilic; Dengue virus; Aedes aegypti; Clusiaceae; Hypericum; Culicidae; Diptera

ImprentaParasitology Research, v. 112, n. 6, p. 2367-2371, 2013.

DescritoresAedes aegypti - Molecular Structure ; Aedes aegypti - Virus ; Aedes aegypti - Dengue ; Aedes aegypti - Public health

Data de Publicação:2013