Larvicidal activity of lipophilic extract of Hypericum carinatum (Clusiaceae) against Aedes aegypti (Diptera: Culicidae) and benzophenones determination
Autor(es): Silva, Flavia Corvello da; Barros, Francisco Maikon; Prophiro, Josiane Somariva; Silva, Onilda Santos da; Pereira, Thiago Nunes; Bordignon, Sergio Ade Loreto; Eifler-Lima, Vera Lucia;Poser, Gilsane Lino von
Resumo: In this study, the larvicidal activity of an enriched fraction of the major lipophilic phenolic compounds from Hypericum carinatum Griseb. (Clusiaceae) was investigated against larvae of Aedes aegypti (Diptera: Culicidae), the main vector of dengue virus in Brazil. The larval mortality rate ranged 37.33 to 72.00 % at concentrations of 66-200 mu g/mL. The effect demonstrated to be dose-dependent. The lethal concentration 50 % and confidence interval were 100 and 88-111 mu g/mL, respectively. The results could be attributed to the presence of cariphenone A and cariphenone B in concentrations of 1.24 plus or minus 0.04 and 0.56 plus or minus 0.01 %, respectively, determined by high-performance liquid chromatography. Besides, the results reinforce the potential of genus Hypericum as source of alternative insecticides.
Palavras-Chave: Molecular structure; Lethal limits; Pesticides; Larvae; Hosts; Mortality causes; Public health; Mortality; Insecticides; Benzophenone; Phenolic compounds; Vectors; Lipophilic; Dengue virus; Aedes aegypti; Clusiaceae; Hypericum; Culicidae; Diptera
Imprenta: Parasitology Research, v. 112, n. 6, p. 2367-2371, 2013.
Descritores: Aedes aegypti - Molecular Structure ; Aedes aegypti - Virus ; Aedes aegypti - Dengue ; Aedes aegypti - Public health
Data de publicação: 2013
