Effects of immunotoxic activity of the major essential oil of Angelica purpuraefolia Chung against Aedes aegypti L
Autor(es): Park, Y. J.; Chung, I. M.; Moon, H. I.
Resumo: The rhizomes parts of Angelica purpuraefolia were extracted and the major essential oils composition and immunotoxic effects were studied. The analyses were conducted by gas chromatography and mass spectroscopy (GC-MS) revealed that the essential oils of A. purpuraefolia. The A. purpuraefolia essential oil (APEO) yield was 0.37%, and GC/MS analysis revealed that its major constituents were b-Phellandrene (32.11%), Nerolidol (10.11%), Pyrimidine derivative (27.33%), Heptadecane (4.33%), and Celorbicol (6.33%). The essential oil had a significant toxic effect against early fourth-stage larvae of Aedes aegypti L with an LC sub(50) value of 31.21 ppm and an LC sub(90) value of 87.22 ppm. The results could be useful in search for newer, safer, and more effective natural immunotoxic agents against A. aegypti.
Palavras-Chave: Pyrimidines; Oil and gas industry; Chromatographic techniques; Rhizomes; Aquatic plants; Major constituents; Toxicity tests; Aquatic insects; Mortality causes; Heptadecane; Chemical composition; Gas chromatography; Larvae; Essential oils; Immune response; Aedes aegypti
Imprenta: Immunopharmacology and Immunotoxicology, v. 32, n. 4, p. 611-613, 2010.
Descritores: Aedes aegypti - Immune response ; Aedes aegypti - Immunology
Data de publicação: 2010
