Effects of a brassinosteroid analogue to mosquito larvae
Autor(es): Davison, G. P.; Restrepo, R.; Martinez, G.; Coll, F.; Leon, O. S.
Resumo: Many plant compounds are able to modulate herbivore growth and reproduction by directly interacting with steroid hormones systems. In insects, several classes of phytochemicals, including brassinosteroids and related substances, interfere with molting and reproduction. The effects of the molting-hormone antagonist pesticide DI-31, a brassinosteroid analogue, on Aedes aegypti mosquito larvae were tested in two different exposure scenarios. After static exposure of first-instar larvae, the calculated NOEC, LOEC, and LC50 values referenced to 19d were 0.03, 0.036, and 0.04mg/mL, respectively. Semistatic exposure of fourth-instar larvae revealed them to be slightly less susceptible than the younger larvae (NOEC 0.03mg/mL, LOEC 0.036mg/mL, LC50 0.049mg/mL referenced to 19 days). In both cases mortality was immediate and larval development was retarded. This study suggests that A. aegypti could be a useful model for the detection of hormonally active substances such as DI-31.
Palavras-Chave: Biological vectors; Human diseases; Lethal effects; Morphogenesis; Sexual reproduction; Larval development; Hormones; Viral diseases; Ecotoxicology; Botanical resources; Pesticides; Inhibitors; Steroids; Mortality; Insecticides; Toxicity testing; Dengue virus; Aedes aegypti
Imprenta: Ecotoxicology and Environmental Safety, v. 56, n. 3, p. 419-424, 2003.
Descritores: Aedes aegypti - Virus ; Aedes aegypti - Sexual ; Aedes aegypti - Dengue
Data de publicação: 2003
