Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti
Autor(es): Yenesew, A; Derese, S; Midiwo, JO; Heydenreich, M; Peter, MG
Resumo: A crude chloroform extract of seeds of Millettia dura Dunn (Leguminosae) showed high activity (LC50 = 3.5 mug ml(-1) at 24 h) against second-instar larvae of the mosquito, Aedes aegypti L (Diptera: Culicidae). The rotenoids, deguelin and tephrosin, isolated from the seeds of this plant also showed potent activities, with LC50 values of 1.6 and 1.4 mug ml(-1) at 24 h, respectively. The related rotenoids millettone and millettosin were inactive at 20 mug ml(-1). Saturation at the B/C ring junction and the presence of methoxy groups at C-2 and/or C-3 in deguelin and tephrosin appear to be important for the observed larvicidal activity. (C) 2003 Society of Chemical Industry.
Palavras-Chave: Millettia dura; Leguminosae; Rotenoids; Tephrosin; Deguelin; Aedes aegypti; Larvicides
Imprenta: Pest Management Science, v. 59, n. 10, p. 1159-1161, 2003
Identificador do objeto digital: 10.1002/ps.740
Descritores: Aedes aegypti - Larvicide
Data de publicação: 2003
