A piperidine amide extracted from Piper longum L. fruit shows activity against Aedes aegypti mosquito larvae
Autor(es): Yang, YC; Lee, SG; Lee, HK; Kim, MK; Lee, SH; Lee, HS
Resumo: Mosquito larvicidal activity of Piper longum fruit-derived materials against the fourth-instar larvae of Aedes aegypti was examined. A crude methanol extract of P. longum fruits was found to be active against the larvae, and the hexane fraction of the methanol extract showed a strong larvicidal activity of 100% mortality. The biologically active component of P. longum fruits was characterized as pipernonaline by spectroscopic analyses. The LC50 value of pipernonaline was 0.25 mg/L. The toxicity of pipernonaline is comparable to that of pirimiphos-methyl as a mosquito larvicide. In tests with available components derived from P. longum, no activity was observed with piperettine, piperine, or piperlongumine.
Palavras-Chave: Aedes aegypti; Piper longum; Pipernonaline; Mosquito larvicidal activity
Imprenta: Journal of Agricultural and Food Chemistry, v. 50, n. 13, p. 3765-3767, 2002
Identificador do objeto digital: 10.1021/jf011708f
Descritores: Aedes aegypti - Larvicide
Data de publicação: 2002
