Predicting Wolbachia potential to knock down dengue virus transmission.
Autor(es): Lambrechts Louis
Resumo: Releasing mosquitoes infected with the intracellular bacteria Wolbachia is a candidate strategy for dengue control that has recently advanced to field-testing. A critical next step is to evaluate the impact of this strategy on dengue epidemiology. A recent study by Ferguson and colleagues presents a mathematical framework to predict the likely effect of mosquitoes carrying Wolbachia on dengue virus transmission. Fitting the mathematical model to empirical data obtained with Wolbachia-infected mosquitoes experimentally challenged with viremic blood from dengue patients indicates that dengue virus transmission could be reduced by a degree that would have a significant impact on public health.
Palavras-Chave: Aedes aegypti; Dengue; Vector competence; Wolbachia
Imprenta: Annals of Translational Medicine, v. 3, n. 19, p. 288, 2015
Identificador do objeto digital: 10.3978/j.issn.2305-5839.2015.09.33.
Descritores: Aedes aegypti - virus ; Aedes aegypti - Transmission ; Aedes aegypti - Dengue ; Aedes aegypti - Epidemiology ; Aedes aegypti - Public health
Data de publicação: 2015