Larvicidal and Pupicidal Activities of Alizarin Isolated from Roots of Rubia cordifolia Against Culex quinquefasciatus Say and Aedes aegypti (L.) (Diptera: Culicidae).
Autor(es): Gandhi M R; Reegan A D; Ganesan P; Sivasankaran K; Paulraj M G; Balakrishna K; Ignacimuthu S; Al-Dhabi N A
Resumo: The mosquitocidal activities of different fractions and a compound alizarin from the methanol extract of Rubia cordifolia roots were evaluated on larvae and pupae of Culex quinquefasciatus Say and Aedes aegypti (L.) (Diptera: Culicidae). Larvae and pupae were exposed to concentrations of 2.5, 5.0, 7.5 and 10Â ppm for fractions and 0.5, 1.0, 1.5 and 2.0Â ppm for compound. After 24Â h, the mortality was assessed and the LC50 and LC90 values were estimated for larvae and pupae. Among the 23 fractions screened, fraction 2 from the methanol extract of R. cordifolia showed good mosquitocidal activity against C. quinquefasciatus and A. aegypti. LC50 and LC90 values of fraction 2 were 3.53 and 7.26Â ppm for C. quinquefasciatus and 3.86 and 8.28Â ppm for A. aegypti larvae, and 3.76 and 7.50Â ppm for C. quinquefasciatus and 3.92 and 8.05Â ppm for A. aegypti pupae, respectively. Further, the isolated compound alizarin presented good larvicidal and pupicidal activities. LC50 and LC90 values of alizarin for larvae were 0.81 and 3.86Â ppm against C. quinquefasciatus and 1.31 and 6.04Â ppm for A. aegypti larvae, respectively. Similarly, the LC50 and LC90 values of alizarin for pupae were 1.97 and 4.79Â ppm for C. quinquefasciatus and 2.05 and 5.59Â ppm for A. aegypti pupae, respectively. The structure of the isolated compound was identified on the basis of spectroscopic analysis and compared with reported spectral data. The results indicated that alizarin could be used as a potential larvicide and pupicide.
Palavras-Chave: Bioassay; Chikungunya; Dengue; Lymphatic filariasis; Zika virus; Mosquito control; Sustainable pest control ;Vector control
Imprenta: Neotropical Entomology, v. 45, n. 4, p. 441-448, 2016
Identificador do objeto digital: 10.1007/s13744-016-0386-x
Descritores: Aedes aegypti - Virus ; Aedes aegypti - Larvicide ; Aedes aegypti - Dengue
Data de publicação: 2016