Guillain - Barre' syndrome following recombinant hepatitis B vaccine and literature review.

Autor(es): Sinsawaiwong S.; Thampanitchawong P.

Resumo: A 17 year-old woman developed progressive quadriparesis with bilateral facial diplegia after immunization with recombinant hepatitis B vaccine 3 days prior. Cerebrospinal fluid analysis revealed acellular fluid with high protein level. The electrodiagnosis was compatible with demyelinating polyneuropathy. Other potential causes of Guillain-Barre' syndrome (GBS) were ruled out. Her motor power gradually improved and returned to normal later. The temporal relationship between GBS and vaccination was suggestive of a vaccine-induced cause. Mechanisms of this very rare complication are proposed with a literature review.

Imprenta: Journal of the Medical Association of Thailand, v. 83, n. 9, p. 1124-1126, 2000

Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Vaccine

Data de publicação: 2000