Episodes of Guillain-Barré syndrome associated with the acute phase of HIV-1 infection and with recurrence of viremia.

Autor(es): de Castro Gleusa; Bastos Patrícia Gomes; Martinez Roberto; de Castro Figueiredo José Fernando

Resumo: We report a severe case of Guillain-Barré syndrome (GBS) characterized by flaccid areflexive tetraplegia and signs of autonomic instability related to acute HIV-1 infection, and the occurrence of relapse episodes coinciding with the detection of HIV-1 RNA in blood during the phase of irregular treatment with antiretroviral agents. The patient has been asymptomatic for 3 years and has an HIV-1 load below the limit of detection. The recurrence of GBS in this case may be related to alterations of the immunologic response caused by disequilibrium in the host-HIV relationship due to the increase in HIV-1 viremia.

Imprenta: Arquivos de Neuro-Psiquiatria, v. 64, n. 3A, p. 606-608, 2006

Identificador do objeto digital: 10.1590/S0004-282X2006000400016

Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - RNA ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Inflammation ; Guillain-Barre Syndrome - Viral infections ; Guillain-Barre Syndrome - Virus ; Guillain-Barre Syndrome - Public health

Data de publicação: 2006