Cytomegalovirus as a frequent cause of Guillain-Barré syndrome

Autor(es): Schmitz H,Enders G

Resumo: In 10 patients with Guillain-Barré syndrome a preceeding cytomegalovirus infection could be demonstrated by virus-specific IgM antibodies that were present in high titers in 9 of the 10 patients in the first serum specimen. The IgM antibodies to cytomegalovirus were detected by a sensitive double" indirect immunofluorescence technique. In most of our cases (8 of 10) the complement-fixing antibody titers had already reached high levels on admission into a hospital, and significant titer changes were not observed. Cytomegalovirus was isolated from the urine of five patients."

Palavras-Chave: Cytomegalovirus; Guillain-Barrd syndrome; IgM antibodies

Imprenta: Journal of Medical Virology, v. 1, n. 1, p. 21-27, 1977

Identificador do objeto digital: 10.1002/jmv.1890010105

Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Serology ; Guillain-Barre Syndrome - Viral infections ; Guillain-Barre Syndrome - Virus ; Guillain-Barre Syndrome - Immunology

Data de publicação: 1977