Assessing grip strength in healthy individuals and patients with immune-mediated polyneuropathies.

Autor(es): Merkies I S,Schmitz P I,Samijn J P,Meché F G,Toyka K V,van Doorn P A


Resumo: Grip strength reference values for a portable dynamometer, the hand-held Vigorimeter, were calculated, and its validity, reliability, and responsiveness were examined in patients with immune-mediated polyneuropathies. We studied 530 healthy controls (age 5-93 years), 113 patients with stable polyneuropathy (83 with Guillain-Barré syndrome [GBS], 22 with chronic inflammatory demyelinating polyneuropathy [CIDP], and 8 with a gammopathy-associated polyneuropathy), and 20 patients with GBS or CIDP and changing clinical conditions (longitudinal group). An arm-disability scale was also assessed. Grip-strength reference values were calculated depending primarily on age and gender. Significant association was obtained between the Vigorimeter and the arm scale (in stable group, Spearman rank: r = -0.52 to -0.62; P or = 0.8) were demonstrated for the Vigorimeter. These results emphasize the clinical usefulness of the Vigorimeter, particularly in patients with immune-mediated polyneuropathies.


Imprenta: Muscle & Nerve, v. 23, n. 9, p. 1393-1401, 2000


Identificador do objeto digital: 10.1002/1097-4598(200009)23:9<1393::AID-MUS10>3.0.CO;2-O


Descritores: Guillain-Barre Syndrome - Immune response ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Immune response ; Guillain-Barre Syndrome - Clinical examination


Data de publicação: 2000