Acute Flaccid paralysis in adults: Our experience.

Autor(es): Kaushik Rupesh,Kharbanda Parampreet S,Bhalla Ashish,Rajan Roopa,Prabhakar Sudesh

Resumo: Acute flaccid paralysis (AFP) is a complex clinical syndrome with a broad array of potential etiologies that vary with age. We present our experience of acute onset lower motor neuron paralysis. One hundred and thirty-three consecutive adult patients presenting with weakness of duration less than four weeks over 12 months period were enrolled. Detailed history, clinical examination, and relevant investigations according to a pre-defined diagnostic algorithm were carried out. The patients were followed through their hospital stay till discharge or death. The mean age was 33.27 (range 13-89) years with male preponderance (67.7%). The most common etiology was neuroparalytic snake envenomation (51.9%), followed by Guillain Barre syndrome (33.1%), constituting 85% of all patients. Hypokalemic paralysis (7.5%) and acute intermittent porphyria (4.5%) were the other important conditions. We did not encounter any case of acute polio mylitis in adults. In-hospital mortality due to respiratory paralysis was 9%. Neuroparalytic snakebite and Guillain Barre syndrome were the most common causes of acute flaccid paralysis in adults in our study.

Palavras-Chave: Guillain Barre syndrome, lower motor neuron, neuroparalytic snakebite, paralysis, weakness

Imprenta: Journal of Emergencies, Trauma, and Shock, v. 7, n. 3, p. 149-154, 2014

Identificador do objeto digital: 10.4103/0974-2700.136847

Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Clinical examination

Data de publicação: 2014