Abnormal proliferation of intraergastoplasmic microfilaments in myelinated schwann cells: ultrastructural study of two cases.

Autor(es): Vallat J M,Vital C,LeBoutet M J,Loubet A,Brechenmacher C


Resumo: We report the ultrastructural findings in superficial peroneal nerve biopsies in two patients, one with idiopathic sensory neuropathy and the other with the Guillain-Barré syndrome and Hodgkin's disease. In addition to demyelination, there was an intense proliferation of microfilaments within numerous vesicles of the endoplasmic reticulum of a great number of myelinated Schwann cells. This abnormality does not appear to have been previously reported in the literature. The mechanisms responsible for this finding are unknown.


Imprenta: Journal of Neuropathology and Experimental Neurology, v. 41, n. 4, p. 460-465, 1982


Identificador do objeto digital: 10.1097/00005072-198207000-00008


Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Cytopathology


Data de publicação: 1982