A neglected Flavivirus: An update on Zika virus in 2016 and the future direction of research.
Autor(es): Bharucha Tehmina; Breuer Judith
Resumo: The 2015-16 global emergence of Zika virus infection (ZIKV) and its putative link with Guillain-Barré Syndrome and microcephaly, at the tail-end of the Ebola epidemic, has provoked unease throughout the international community. The World Health Organisation (WHO) declared ZIKV a public health emergency on 1(st) February 2016, but at the time of writing suggest there is still insufficient evidence that ZIKV is independently responsible for any serious complications. Our current understanding of this arthropod-borne Flavivirus is still at an early stage. The first reported human infections were sixty years ago, and until the first outbreak in Micronesia in 2007, there were only fourteen documented cases. Nonetheless there are parallels that we can draw from our understanding of other related arbo-flaviviruses, such as dengue, Japanese encephalitis and West Nile viruses. This article provides a focussed review of the literature on ZIKV to date, with perspectives on the direction of future research. This article is protected by copyright. All rights reserved.
Palavras-Chave: Arbovirus, Emerging Infection, Flavivirus, Public health
Imprenta: Neuropathology and Applied Neurobiology, 2016
Identificador do objeto digital: 10.1111/nan.12326
Descritores: Guillain-Barre Syndrome - Dengue ; Guillain-Barre Syndrome - Epidemic ; Guillain-Barre Syndrome - Microcephaly ; Guillain-Barre Syndrome - Public health
Data de publicação: 2016
