A case of anti-GA1 antibody-positive Fisher syndrome with elevated tau protein in cerebrospinal fluid.
Autor(es): Oyazato Yoshinobu,Shiihara Takashi,Kusunoki Susumu,Adachi Masao,Ohnishi Noriko,Taniguchi Hiroaki,Nishiyama Atsushi,Watanabe Aika,Kobayashi Mitsuro,Kamioka Ichiro
Resumo: We describe a boy with Fisher syndrome. He presented the typical symptoms of Fisher syndrome, including external ophthalmoplegia, abnormality of convergence, and areflexia, after an episode of Campylobacter enterocolitis. Atypically, however, anti-GA1 antibody was detected in his serum, though anti-GQ1b and anti-GT1a antibodies were not. In addition, the tau protein level in his cerebrospinal fluid was elevated. Generally, Fisher syndrome is a self-limiting disease and has a good prognosis. In our patient, however, mild diplopia and areflexia persisted 6 months after their onset. Here, we report on the first Fisher syndrome patient with anti-GA1 antibody in the serum and elevated tau protein in the cerebrospinal fluid.
Imprenta: Brain & Development, v. 34, n. 4, p. 329-332, 2012
Identificador do objeto digital: 10.1016/j.braindev.2011.06.007
Descritores: Guillain-Barre Syndrome - Biosynthesis ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Protein synthesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Immunology
Data de publicação: 2012
