Progress in inflammatory neuropathy -the legacy of Dr Jack Griffin.
Autor(es)Feldman Eva L.; Hughes Richard A. C.; Willison Hugh J.
ResumoThe past quarter of a century has brought incredible advances in our understanding of inflammatory neuropathies, and the insights into Guillain-Barré syndrome (GBS) began in the 1990s with the seminal work of Dr Jack Griffin and his colleagues. In this essay, we provide a tribute to Jack, and review the recent progress in a field that he termed his personal favourite. In particular, we discuss the new developments in our understanding and diagnosis of inflammatory neuropathies, the recent emergence of the node of Ranvier and the paranode as sites of intensive investigation, and the mechanistic evidence that is providing a platform for therapeutic development studies.
ImprentaNature Reviews, v. 11, n. 11, p. 646-650, 2015
Identificador do Objeto Digital10.1038/nrneurol.2015.192
DescritoresGuillain-Barre Syndrome - Biosynthesis ; Guillain-Barre Syndrome - Cytopathology
Data de Publicação:2015
