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Lymphocyte sensitization to nervous tissues and muscle in patients with the Guillain-Barré syndrome.

Autor(es)Caspary E. A.; Currie S.; Walton J. N.; Field E. J.
ResumoBy means of an electrophoretic method lymphocytes from patients with the Guillain-Barré syndrome (`acute idiopathic polyneuritis') have been shown to be sensitized to both encephalitogenic factor (EF) and a similar basic protein prepared from human sciatic nerve (SNBP). Sensitization was more marked in the acute stage of the disorder during which there also appeared to be a degree of sensitization to muscle. The results are consistent with the view that lymphocytic infiltration of peripheral nerves in the condition is of pathogenetic significance.
ImprentaJournal of Neurology, Neurosurgery, and Psychiatry, v. 34, n. 2, p. 179-181, 1971
Identificador do Objeto Digital10.1136/jnnp.34.2.179
DescritoresGuillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Immunology
Data de Publicação:1971