Lymphocyte sensitization to nervous tissues and muscle in patients with the Guillain-Barré syndrome.
Autor(es): Caspary E. A.; Currie S.; Walton J. N.; Field E. J.
Resumo: By means of an electrophoretic method lymphocytes from patients with the Guillain-Barré syndrome (`acute idiopathic polyneuritis') have been shown to be sensitized to both encephalitogenic factor (EF) and a similar basic protein prepared from human sciatic nerve (SNBP). Sensitization was more marked in the acute stage of the disorder during which there also appeared to be a degree of sensitization to muscle. The results are consistent with the view that lymphocytic infiltration of peripheral nerves in the condition is of pathogenetic significance.
Imprenta: Journal of Neurology, Neurosurgery, and Psychiatry, v. 34, n. 2, p. 179-181, 1971
Identificador do objeto digital: 10.1136/jnnp.34.2.179
Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Immunology
Data de publicação: 1971
