Autor(es): Araga S.; Kagimoto H.; Adachi A.; Funamoto K.; Inoue K.; Takahashi K.

Resumo: The kappa/lambda (kappa/lambda) ratios of IgG, IgA and IgM in the cerebrospinal fluid (CSF) and in the sera of 10 patients with Guillain-Barré syndrome were analyzed. The kappa/lambda ratios of IgG, IgA and IgM in the CSF and in the serum were not significantly different between the acute and the late stages of Guillain-Barré syndrome nor between Guillain-Barré syndrome and the normal controls. In the CSF, however, the concentration of albumin, IgG, IgA and IgM in the acute phases of Guillain-Barré syndrome were significantly higher than in the normal controls. These results suggest that in Guillain-Barré syndrome, the increase of immunoglobulins may not be due to intrathecal synthesis and therefore there are no significant changes in the kappa/lambda ratios in the CSF.

Imprenta: Japanese Journal of Medicine, v. 30, n. 2, p. 118-122, 1991

Identificador do objeto digital: 10.2169/internalmedicine1962.30.118

Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Immunology

Data de publicação: 1991