Plasma exchange in Guillain-Barré syndrome: effect on anti-peripheral nerve myelin antibodies.
Autor(es)Vedeler C. A.; Nyland H.
ResumoIncreased levels of anti-peripheral nerve myelin (anti-PNM) antibodies were demonstrated by ELISA in serum from 4 of 7 patients with Guillain-Barré syndrome (GBS). Treatment with plasma exchange (PE) was performed and 6 of the 7 patients showed clinical improvement with marked increase in muscular strength. One patient, however, continued to deteriorate during the treatment. No correlation between clinical improvement and levels of anti-PNM antibodies was observed. Whether the antibodies are of pathogenetic importance in GBS is therefore still unknown.
ImprentaActa Neurologica Scandinavica, v. 82, n. 2, p. 147-149, 1990
Identificador do Objeto Digital10.1111/j.1600-0404.1990.tb01606.x
DescritoresGuillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Immunology
Data de Publicação:1990
