Neurophysiology in Guillain-Barré syndrome

Autor(es): Kokubun Norito


Resumo: The electrodiagnostic features for the demyelinating and axonal subtypes of Guillain-Barré syndrome (GBS) were described. In the early stage of demyelinating GBS, the most prominent neurophysiologic feature is the patchy demyelination in the peripheral nerves. Conduction slowing presents in the clinical recovery stage, which indicates the conduction slowing is due to mainly remyelination. Axonal GBS shows reversible conduction failure", as well as primary axonal degeneration. "Reversible conduction failure" is thought to be the most common cause of the underestimation of axonal GBS. The electrodiagnostic criteria for GBS subtypes should be revised based on the knowledge acquired in recent years."


Imprenta: Brain and nerve = Shinkei kenkyu? no shinpo, v. 67, n. 11, p. 1321-1328, 2015


Identificador do objeto digital: 10.11477/mf.1416200302


Descritores: Guillain-Barre Syndrome - Cell


Data de publicação: 2015