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Case report; A case of anti-GD1b antibody positive pure motor form Guillain-Barré syndrome with good response to combined IVIg and steroid therapy

Autor(es)Fujimoto Takeshi,Fukuda Yasuo,Eguchi Katsumi,Kusunoki Susumu
ResumoA 43-year-old woman diagnosed with pure movement Guillain-Barré syndrome accompanied by conduction block without accompanied by ataxia or sensory disturbance, with a preceding infection of upper respiratory symptoms. Two weeks after the start of combination therapy of mass immunoglobulin and steroid mini pulse, limb muscle strength improved and conduction block finding disappeared. IgG anti-GD1b antibody was single positive in the serum. Although anti-GD1b antibody has been reported to be related to ataxia and sensory disorders from the past, in this case there was a difference in specificity of the antibody against GD1b, and it was inferred that there is a difference in the appearance of these antibodies.
Palavras-ChavePure exercise Guillain-Barré syndrome; Anti -ganglioside antibody; GD1b
ImprentaNihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, v. 100, n. 6, p. 1651-1653, 2011
Identificador do Objeto Digital10.2169/naika.100.1651
DescritoresGuillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Immunology
Data de Publicação:2011