An elderly case of chronic inflammatory demyelinating polyneuropathy with acute onset in the course of diabetes mellitus
Autor(es): Katsuoka H,Mimori Y,Mitsuoka T,Morino H,Kurokawa K,Harada A,Nakamura S
Resumo: A 77-year-old man was admitted because of muscle weakness in both upper and lower extremities. Diabetes mellitus was diagnosed in 1988 and he had been treated by oral hypoglycemic agents. He had a common cold at the end of January, 1997. Muscle weakness appeared in the upper extremities, followed by the lower extremities at the end of February. No sensory disturbance or dysuria was recognized. Nerve conduction study revealed distally dominant demyelinating polyneuropathy. Guillain-Barré's syndrome was diagnosed and he recovered completely following immunological absorption therapy (IAT). However, he had quadriplegia again at the end of April. He was treated by IAT combined with corticosteroid and has shown no relapse. In June, 1997, gastric cancer was detected by upper gastrointestinal fiberscopy and subtotal gastrectomy was performed. Judging from this clinical course, this case seems to be chronic inflammatory demyelinating polyneuropathy (CIDP) with acute onset. Many kinds of causes often contribute to the pathogenesis of neuropathy in the elderly. So in cases of progression or worsening, we should consider such possibilities and it is necessary not to exclude treatable causes of neuropathy.
Palavras-Chave: Chronic inflammatory demyelinating polyneuropathy; Diabetes mellitus; Gastric cancer; Nerve conduction study
Imprenta: Nihon Ronen Igakkai Zasshi. Japanese journal of geriatrics, v. 36, n. 7, p. 495-498, 1999
Identificador do objeto digital: 10.3143/geriatrics.36.495
Descritores: Guillain-Barre Syndrome - Pathogenesis
Data de publicação: 1999
