A case of acute hepatitis a complicated by Guillain-Barré syndrome
Autor(es): Bae Yun Jeong,Kim Kang Mo,Kim Kwang Kuk,Rho Jae Hyung,Lee Hyun Ki,Lee Yung Sang,Suh Dong Jin
Resumo: We report here a case of acute hepatitis A, which was complicated by Guillain-Barré syndrome (GBS). A 32-year old male admitted to our hospital with the symptoms of acute hepatitis and was diagnosed to have acute hepatitis A with positive IgM anti hepatitis A virus antibody. On 9th day after the onset of jaundice, acute progressive, ascending, symmetric motor paralysis were developed and eventually respiratory failure ensued. Cerebrospinal fluid analysis showed albumino-cytologic dissociation and nerve conduction velocity test suggested a polyradiculopathy. He was diagnosed to have GBS and treated with intravenous immunoglobulin and required a ventilatory support. After 90 hospital days, he recovered in ambulatory condition with the aid of crutches. The clinical course, prognosis and the outcome of neuropathic symptoms of GBS following acute hepatitis A were relatively poor in our case.
Palavras-Chave: Hepatitis A; Guillain-Barré syndrome; Immunoglobulins; Complication
Imprenta: The Korean Journal of Hepatology, v. 13 n. 2, p. 228-233, 2007.
Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Viral infections ; Guillain-Barre Syndrome - Virus
Data de publicação: 2007
