Wolbachia pipientis: An exp-ing bag of tricks to explore for disease control
Autor(es): Cook Peter E, McGraw Elizabeth A
Resumo: Wolbachia pipientis are maternally inherited, endosymbiotic bacteria that are widespread among insects. Two recent studies have demonstrated that Wolbachia inhibits the ability of medically significant pathogens, including filarial nematodes, dengue virus - Plasmodium to form infections in the mosquito vector, Aedes aegypti. We highlight the added value of these traits for Wolbachia based biocontrol strategies - evaluate the evidence for the idea that the insect immune response is responsible for the pathogen inhibition.
Imprenta: Trends in Parasitology, v. 26, n. 8, p. 373-375, 2010
Identificador do objeto digital: 10.1016/j.pt.2010.05.006
Descritores: Chikungunya virus - Flaviviridae ; Chikungunya virus - Immune response ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Immune response ; Chikungunya Virus - Virus ; Chikungunya virus - Dengue ; Chikungunya virus - Immunology ; Chikungunya virus - Public health
Data de publicação: 2010