Vector competence of Aedes aegypti and Aedes vittatus (Diptera: Culicidae) from Senegal and Cape Verde archipelago for West African lineages of Chikungunya virus
Autor(es): Diagne Cheikh T, Faye Oumar, Guerbois Mathilde, Knight Rachel, Diallo Diawo, Faye Ousmane, Ba Yamar, Dia Ibrahima, Faye Ousmane, Weaver Scott C, Sall Amadou A, Diallo Mawlouth
Resumo: To assess the risk of emergence of chikungunya virus (CHIKV) in West Africa, vector competence of wild-type, urban, - non-urban Aedes aegypti - Ae. vittatus from Senegal - Cape Verde for CHIKV was investigated. Mosquitoes were fed orally with CHIKV isolates from mosquitoes (ArD30237), bats (CS13-288), - humans (HD180738). After 5, 10, - 15 days of incubation following an infectious blood meal, presence of CHIKV RNA was determined in bodies, legs/wings, - saliva using real-time reverse transcription-polymerase chain reaction. Aedes vittatus showed high susceptibility (50-100%) - early dissemination - transmission of all CHIKV strains tested. Aedes aegypti exhibited infection rates ranging from 0% to 50%. Aedes aegypti from Cape Verde - Kedougou, but not those from Dakar, showed the potential to transmit CHIKV in saliva. Analysis of biology - competence showed relatively high infective survival rates for Ae. vittatus - Ae. aegypti from Cape Verde, suggesting their efficient vector capacity in West Africa.
Imprenta: The American Journal of Tropical Medicine and Hygiene, v. 91, n. 3, p. 635-641, 2014
Identificador do objeto digital: 10.4269/ajtmh.13-0627
Descritores: Chikungunya virus - Cytopathology ; Chikungunya virus - Molecular structure ; Chikungunya virus - Pathogenesis ; Chikungunya virus - RNA ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya virus - Real Time PCR ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health
Data de publicação: 2014
