Vector competence of Aedes aegypti and Aedes vittatus (Diptera: Culicidae) from Senegal and Cape Verde archipelago for West African lineages of Chikungunya virus
Autor(es)Diagne Cheikh T, Faye Oumar, Guerbois Mathilde, Knight Rachel, Diallo Diawo, Faye Ousmane, Ba Yamar, Dia Ibrahima, Faye Ousmane, Weaver Scott C, Sall Amadou A, Diallo Mawlouth
ResumoTo assess the risk of emergence of chikungunya virus (CHIKV) in West Africa, vector competence of wild-type, urban, - non-urban Aedes aegypti - Ae. vittatus from Senegal - Cape Verde for CHIKV was investigated. Mosquitoes were fed orally with CHIKV isolates from mosquitoes (ArD30237), bats (CS13-288), - humans (HD180738). After 5, 10, - 15 days of incubation following an infectious blood meal, presence of CHIKV RNA was determined in bodies, legs/wings, - saliva using real-time reverse transcription-polymerase chain reaction. Aedes vittatus showed high susceptibility (50-100%) - early dissemination - transmission of all CHIKV strains tested. Aedes aegypti exhibited infection rates ranging from 0% to 50%. Aedes aegypti from Cape Verde - Kedougou, but not those from Dakar, showed the potential to transmit CHIKV in saliva. Analysis of biology - competence showed relatively high infective survival rates for Ae. vittatus - Ae. aegypti from Cape Verde, suggesting their efficient vector capacity in West Africa.
ImprentaThe American Journal of Tropical Medicine and Hygiene, v. 91, n. 3, p. 635-641, 2014
Identificador do Objeto Digital10.4269/ajtmh.13-0627
DescritoresChikungunya virus - Cytopathology ; Chikungunya virus - Molecular structure ; Chikungunya virus - Pathogenesis ; Chikungunya virus - RNA ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya virus - Real Time PCR ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health
Data de Publicação:2014
