Autor(es): Sarkar J K, Chatterjee S N, Chakravarty S K

Resumo: A new type of fever characterized by haemorrhagic manifestations or shock or both broke out in Calcutta as a double-peak epidemic in 1963. The epidemic was almost as severe in 1964 as in 1963, but in 1965 the morbidity was much less. 302 cases diagnosed clinically as haemorrhagic fever were virologically and serologically investigated during this period. 55% had arthralgia, 18% had skin rash, 14% had lymphadenitis and 28% had frank haemorrhage. Chikungunya virus, apparently a new one in India, was isolated from 64 patients and dengue virus (3 type 2, 2 type 4, and one probably type 1) from 6. In addition to those, a number of cases were diagnosed serologically as either chikungunya or Group B arbovirus (probably dengue) infection. In many of the cases with severe haemorrhagic manifestations or shock, dengue virus aetiology could be established, and in some, chikungunya aetiology without any evidence of simultaneous dengue infection could be shown. 10 of the 302 patients died.

Imprenta: Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 61, n. 5, p. 725-735, 1967

Identificador do objeto digital: 10.1016/0035-9203(67)90142-3

Descritores: Chikungunya virus - Flaviviridae ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Serology ; Chikungunya virus - Viral infections ; Chikungunya virus - Serology ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue ; Chikungunya virus - Epidemiology ; Chikungunya virus - Immunology ; Chikungunya virus - Public health

Data de publicação: 1967