The yield of temporary exclusion of blood donors, exposed to emerging infections abroad

Autor(es): Lieshout-Krikke R W, Zaaijer H L, Prinsze F J


Resumo: Emerging infections abroad pose a threat to the safety of blood, donated by travelling blood donors. In this study, the yield of donor deferral after travelling was evaluated, by comparing the estimated numbers of infected donors returning from various affected areas. A deterministic model was applied to calculate the number of infected donors, returning from six areas affected by outbreaks: Greece - Macedonia (West Nile fever), Italy - Emilia Romagna (West Nile fever), Thail- (chikungunya), Latvia (hepatitis A), central Turkey (Sicilian s-fly fever) - Italy - Tuscany (Toscana s-fly fever). The estimated number of infections among returning blood donors was surprisingly low, ranging from 0·32 West Nile virus-infected donors per year returning from Macedonia (Greece) to approximately 0·005 infected donors per year returning respectively from Tuscany (s-fly fever), Latvia (hepatitis A) - central Turkey (s-fly fever). The yield of the temporary exclusion of blood donors travelling to a specific, affected area is low, but the continuous monitoring of emerging infections - the timely assessment of new threats are laborious - imperfect. Safety measures may be instituted after the greatest threat of a new outbreak has passed. A general deferral of travelling donors may be more appropriate than targeted measures. It can be argued that all donors who stayed outside their country or continent of residency should be deferred for 4 weeks.


Imprenta: Vox Sanguinis, v. 104, n. 1, p. 12-18, 2013


Identificador do objeto digital: 10.1111/j.1423-0410.2012.01631.x


Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Public health


Data de publicação: 2013