The first dominant co-circulation of both Dengue and Chikungunya viruses during the post-monsoon period of 2010 in Delhi, India
Autor(es): Singh P, Mittal V, Rizvi M M A, Chhabra M, Sharma P, Rawat D S, Bhattacharya D, Chauhan L S, Rai A
Resumo: Independent outbreaks of dengue virus (DENV) infection - sporadic cases of chikungunya virus (CHIKV) have been recorded in the metropolitan city of Delhi on several occasions in the past. However, during a recent 2010 arboviral outbreak in Delhi many cases turned negative for DENV. This prompted us to use duplex reverse transcriptase-polymerase chain reaction (D-RT-PCR) to establish the aetiology of dengue/chikungunya through sequencing of CprM - E1 genes of dengue - chikungunya viruses. Interestingly, for the first time, both DENV - CHIKV co-circulated simultaneously - in equally dominant proportion during the post-monsoon period of 2010. DENV-1 genotype III - the East Central South African genotype of CHIKV were associated with post-monsoon spread of these viruses.
Imprenta: Epidemiology and Infection, v. 140, n. 7, p. 1337-1342, 2012
Identificador do objeto digital: 10.1017/S0950268811001671
Descritores: Chikungunya virus - Biochemistry ; Chikungunya virus - DNA ; Chikungunya virus - Flaviviridae ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - Viral infections ; Chikungunya virus - RT-PCR ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health
Data de publicação: 2012
