Autor(es): Parola Philippe, de Lamballerie Xavier, Jourdan Jacques, Rovery Clarisse, Vaillant Véronique, Minodier Philippe, Brouqui Philippe, Flahault Antoine, Raoult Didier, Charrel Rémi N

Resumo: Chikungunya virus (CHIKV) emerged in Indian Ocean isl-s in 2005 - is causing an ongoing outbreak that involves >260,000 patients, including travelers returning home from these isl-s. We investigated cases in 4 patients returning from Mayotte - Reunion Isl-s with CHIKV infection - a nurse infected in metropolitan France after direct contact with the blood of a traveler. Four patients had tenosynovitis - pain at wrist pressure, - 1 had life-threatening manifestations. Four CHIKV strains were isolated, including 1 from the patient with the autochthonous case. The complete genomic sequence identified a new CHIKV variant emerging from the East/ central African evolutionary lineage. Aedes albopictus, the implicated vector of CHIKV in Indian Ocean isl-s, has dispersed worldwide in recent decades. High viral loads in patients returning from Indian Ocean isl-s to countries where Ae. albopictus is prevalent may be a source of epidemics.

Imprenta: Emerging Infectious Diseases, v. 12, n. 10, p. 1493-1499, 2006

Identificador do objeto digital: 10.3201/eid1210.060610

Descritores: Chikungunya virus - Molecular structure ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Viral infections ; Chikungunya virus - Molecular methods ; Chikungunya virus - RT-PCR ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Epidemic ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health

Data de publicação: 2006

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